A retrospective study of ensartinib-treated ALK-positive locally advanced or metastatic NSCLC patients in China.

ABSTRACT:

Aim

This retrospective study aimed to assess the efficacy and safety of ensartinib in Chinese patients with ALK-positive advanced NSCLC in real-world clinical practice.

Methods

Clinical data from ALK-positive NSCLC patients treated with ensartinib in China were collected and analyzed. Efficacy end points included objective response rate and progression-free survival. Safety profiles were also evaluated.

Results

A total of 682 patients were included in this study. The study demonstrated promising efficacy with an objective response rate of 54.0%, and the median progression-free survival was not estimable. Ensartinib exhibited a manageable safety profile with treatment-related adverse events (TRAEs) consistent with prior clinical trials. The most common TR

SUBMITTER: Yuan X 

PROVIDER: S-EPMC10793637 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature