Magnetic resonance-guided laser interstitial thermal therapy vs. open surgery for drug-resistant mesial temporal lobe epilepsy: A propensity score matched retrospective cohort study.

ABSTRACT:

Background

Magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) and traditional open surgery (OS) are effective and safe options for patients with drug-resistant mesial temporal lobe epilepsy (DR-mTLE). However, their superiority in seizure control and preservation of functional abilities remains unclear. This study aimed to compare the surgical outcomes of MRgLITT and OS.

Materials and methods

This multicenter retrospective cohort study included patients with DR-mTLE who underwent MRgLITT or OS at three centers between 2015 and 2023. The data on patient demographics, presurgical non-invasive evaluation, stereoelectroencephalography (SEEG) implantation, memory alteration, and seizure outcomes were collected. A propensity score matching (PSM) analysis was co

SUBMITTER: Mo J 

PROVIDER: S-EPMC10793731 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature