Impact of antibiotic-coated sutures on surgical site infections: a second-order meta-analysis.

ABSTRACT:

Background

Surgical site infections (SSIs) pose a global challenge, impacting patients and healthcare expenditures. This second-order meta-analysis endeavors to assess the efficacy of antibiotic sutures in averting SSIs by amalgamating data from various meta-studies.

Materials and methods

This research adhered to the PRISMA 2020 guidelines. The quality and comprehensiveness of the encompassed meta-analyses were assessed through the QUOROM checklist and AMSTAR techniques. The primary study overlap was evaluated via measures such as pairwise intersection heat maps, Corrected Covered Area (CCA), and the citation matrix of evidence. The statistical power at the study level was determined utilizing the meta-meta package. Data synthesis employed random and fixed effects models at

SUBMITTER: Suleiman AS 

PROVIDER: S-EPMC10793740 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature