Unknown

Dataset Information

0

Successes and Failures of Combined Modalities in Upper Gastrointestinal Malignancies: New Directions.


ABSTRACT: Upper gastrointestinal malignancies generally have moderate to poor cure rates, even in the earliest stages, thereby implying that both local and systemic treatments have room for improvement. Therapeutic options are broadening, however, with the development of new immunotherapies and targeted agents, which can have synergistic effects with radiotherapy. Here we discuss the current state of combined modality therapy for upper gastrointestinal malignancies, specifically recent successes and setbacks in trials of radiation therapy with targeted therapies, vaccines, immunotherapies, and chemotherapies.

SUBMITTER: Jamorabo DS 

PROVIDER: S-EPMC10794083 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature

altmetric image

Publications

Successes and Failures of Combined Modalities in Upper Gastrointestinal Malignancies: New Directions.

Jamorabo Daniel S DS   Lin Steven H SH   Jabbour Salma K SK  

Seminars in radiation oncology 20160525 4


Upper gastrointestinal malignancies generally have moderate to poor cure rates, even in the earliest stages, thereby implying that both local and systemic treatments have room for improvement. Therapeutic options are broadening, however, with the development of new immunotherapies and targeted agents, which can have synergistic effects with radiotherapy. Here we discuss the current state of combined modality therapy for upper gastrointestinal malignancies, specifically recent successes and setba  ...[more]

Similar Datasets

| S-EPMC9859734 | biostudies-literature
| S-EPMC6992220 | biostudies-literature
| S-EPMC5347918 | biostudies-literature
| S-EPMC9708951 | biostudies-literature
| S-EPMC5925434 | biostudies-literature
| S-EPMC9695435 | biostudies-literature
| S-EPMC9634418 | biostudies-literature
| S-EPMC8968113 | biostudies-literature
| S-EPMC5074862 | biostudies-literature
| S-EPMC4000701 | biostudies-literature