Research progress and application of single-cell sequencing in head and neck malignant tumors.

ABSTRACT: Single-cell sequencing (SCS) is a technology that separates thousands of cells from the organism and accurately analyzes the genetic material expressed in each cell using high-throughput sequencing technology. Unlike the traditional bulk sequencing approach, which can only provide the average value of a cell population and cannot obtain specific single-cell data, single-cell sequencing can identify the gene sequence and expression changes of a single cell, and reflects the differences between genetic material and protein between cells, and ultimately the role played by the tumor microenvironment. single-cell sequencing can further explore the pathogenesis of head and neck malignancies from the single-cell biological level and provides a theoretical basis for the clinical diagnosis and trea

SUBMITTER: Qu S 

PROVIDER: S-EPMC10794142 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature