Prenatal paternal anxiety symptoms predict child DHEA levels and internalizing symptoms during adrenarche.

ABSTRACT:

Introduction

This study examined (1) whether measures of paternal anxious and depressive symptoms collected prenatally and during a follow-up assessment when the child was in middle childhood, predict child neuroendocrine outcomes, and (2) whether neuroendocrine outcomes are intermediate factors between paternal mental health and child cognitive/behavioral outcomes. Middle childhood coincides with increased autonomy as the child transitions into grade school, and with adrenarche, as the maturing adrenal gland increases secretion of dehydroepiandrosterone (DHEA) and its sulfated metabolite (DHEA-S), hormones that are implicated in corticolimbic development which regulate emotions and cognition.

Methods

Participants were recruited from a subsample of a large prospective birth

SUBMITTER: Jones SL 

PROVIDER: S-EPMC10794355 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature