Current trends and future prospects of drug repositioning in gastrointestinal oncology.

ABSTRACT: Gastrointestinal (GI) cancers comprise a significant number of cancer cases worldwide and contribute to a high percentage of cancer-related deaths. To improve survival rates of GI cancer patients, it is important to find and implement more effective therapeutic strategies with better prognoses and fewer side effects. The development of new drugs can be a lengthy and expensive process, often involving clinical trials that may fail in the early stages. One strategy to address these challenges is drug repurposing (DR). Drug repurposing is a developmental strategy that involves using existing drugs approved for other diseases and leveraging their safety and pharmacological data to explore their potential use in treating different diseases. In this paper, we outline the existing therapeutic str

SUBMITTER: Fatemi N 

PROVIDER: S-EPMC10794567 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature