Postoperative systemic inflammatory response syndrome predicts increased mortality in patients after elective craniotomy.

ABSTRACT:

Introduction

Patients undergoing craniotomy are at high risk of perioperative morbidity and mortality due to excessive inflammatory responses. The purpose of the present study is to evaluate the prognostic utility of postoperative systemic inflammatory response syndrome (SIRS) in patients undergoing craniotomy.

Methods

We performed a retrospective cohort study of patients who underwent craniotomy between January 2011 and March 2021. SIRS was diagnosed based on two or more criteria (hypo-/hyperthermia, tachypnea, leukopenia/leukocytosis, tachycardia). We used univariate and multivariate analysis for the development of SIRS with postoperative 30-day mortality.

Results

Of 12,887 patients who underwent craniotomy, more than half of the patients (n = 6,725; 52.2%) d

SUBMITTER: Peng L 

PROVIDER: S-EPMC10794578 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature