Epidemiology and molecular analyses of respiratory syncytial virus in the 2021-2022 season in northern Italy.

ABSTRACT:

Background

Human respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory tract infection among infants and young children worldwide, with seasonal peaks in January and February. This study aimed to characterize the RSV samples from a pediatric cohort in the 2021-2022 season in Italy.

Methods

In total, 104 samples were collected from pediatric patients attending the "Vittore Buzzi" Children's Hospital in Milan, Italy in the 2021-2022 season. RT-PCR and next-generation sequencing were used to discriminate subgroups and obtain whole genomes. Maximum likelihood and Bayesian phylogenetic methods were used to analyze Italian sequences in the European contest and date Italian clusters.

Results

The median age was 78 days, and 76.9% of subjects requir

SUBMITTER: Lai A 

PROVIDER: S-EPMC10794773 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature