Magnetic Graphene Oxide Nanocomposites for Selective miRNA Separation and Recovery.

ABSTRACT: In this study, we developed magnetic graphene oxide composites by chemically attaching Fe₃O₄ nanoparticles to graphene oxide nanosheets. Characterization techniques, including Fourier transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), Raman spectroscopy, thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), and transmission electron microscopy (TEM), confirmed the successful synthesis of Fe₃O₄@GO composites with desirable properties. The resulting composites exhibited superparamagnetic behavior, solubility, and compatibility for efficient miRNA separation. Using miR-29a as a model, we demonstrated the effective binding of miR-29a to the magnetic graphene oxide (GO) composites

SUBMITTER: Uten S 

PROVIDER: S-EPMC10795033 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature