Refining and illuminating acetogenic Eubacterium strains for reclassification and metabolic engineering.

ABSTRACT:

Background

The genus Eubacterium is quite diverse and includes several acetogenic strains capable of fermenting C1-substrates into valuable products. Especially, Eubacterium limosum and closely related strains attract attention not only for their capability to ferment C1 gases and liquids, but also due to their ability to produce butyrate. Apart from its well-elucidated metabolism, E. limosum is also genetically accessible, which makes it an interesting candidate to be an industrial biocatalyst.

Results

In this study, we examined genomic, phylogenetic, and physiologic features of E. limosum and the closest related species E. callanderi as well as E. maltosivorans. We sequenced the genomes of the six Eubacterium strains 'FD' (DSM 3662^T), 'Marburg' (DSM 3468), '2A'

SUBMITTER: Flaiz M 

PROVIDER: S-EPMC10795377 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature