Whole-genome resequencing of major populations revealed domestication-related genes in yaks.

ABSTRACT:

Background

The yak is a symbol of the Qinghai-Tibet Plateau and provides important basic resources for human life on the plateau. Domestic yaks have been subjected to strong artificial selection and environmental pressures over the long-term. Understanding the molecular mechanisms of phenotypic differences in yak populations can reveal key functional genes involved in the domestication process and improve genetic breeding.

Material and method

Here, we re-sequenced 80 yaks (Maiwa, Yushu, and Huanhu populations) to identify single-nucleotide polymorphisms (SNPs) as genetic variants. After filtering and quality control, remaining SNPs were kept to identify the genome-wide regions of selective sweeps associated with domestic traits. The four methods (π, XPEHH, iHS, and XP-nSL) w

SUBMITTER: Peng W 

PROVIDER: S-EPMC10795378 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature