Impact of Thyroid Status on Incident Kidney Dysfunction and Chronic Kidney Disease Progression in a Nationally Representative Cohort.

ABSTRACT:

Objective

To examine the relationship between thyroid status and incident kidney dysfunction/chronic kidney disease (CKD) progression.

Patients and methods

We examined incident thyroid status, ascertained by serum thyrotropin (TSH) levels measured from January 1, 2007, through December 31, 2018, among 4,152,830 patients from the Optum Labs Data Warehouse, containing deidentified retrospective administrative claims data from a large national health insurance plan and electronic health record data from a nationwide network of provider groups. Associations of thyroid status, categorized as hypothyroidism, euthyroidism, or hyperthyroidism (TSH levels >5.0, 0.5-5.0, and <0.5 mIU/L, respectively), with the composite end point of incident kidney dysfunction in patients without base

SUBMITTER: You AS 

PROVIDER: S-EPMC10795379 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature