Metagenomic analysis of healthy and diseased peri-implant microbiome under different periodontal conditions: a cross-sectional study.

ABSTRACT:

Background

Peri-implantitis is a polybacterial infection that can lead to the failure of dental implant rehabilitation. This study aimed to profile the microbiome of the peri-implant plaque and estimate the effect of periodontitis on it among 40 Chinese participants with dental implant prostheses and presenting with varying peri-implant and periodontal health states.

Methods

Submucosal plaque samples were collected from four distinct clinical categories based on both their implant and periodontal health status at sampling point. Clinical examinations of dental implant and remaining teeth were carried out. Metagenomic analysis was then performed.

Results

The microbiome of the peri-implantitis sites differed from that of healthy implant sites, both taxonomically and fun

SUBMITTER: Song L 

PROVIDER: S-EPMC10795403 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature