Ontology highlight
ABSTRACT:
SUBMITTER: Schulte R
PROVIDER: S-EPMC10795821 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Schulte Reinhard R Johnstone Carol C Boucher Salime S Esarey Eric E Geddes Cameron G R CGR Kravchenko Maksim M Kutsaev Sergey S Loo Billy W BW Méot François F Mustapha Brahim B Nakamura Kei K Nanni Emilio A EA Obst-Huebl Lieselotte L Sampayan Stephen E SE Schroeder Carl B CB Sheng Ke K Snijders Antoine M AM Snively Emma E Tantawi Sami G SG Van Tilborg Jeroen J
Applied sciences (Basel, Switzerland) 20230417 8
The general concept of radiation therapy used in conventional cancer treatment is to increase the therapeutic index by creating a physical dose differential between tumors and normal tissues through precision dose targeting, image guidance, and radiation beams that deliver a radiation dose with high conformality, e.g., protons and ions. However, the treatment and cure are still limited by normal tissue radiation toxicity, with the corresponding side effects. A fundamentally different paradigm fo ...[more]