Differences in boundary behavior in the 3D vertex and Voronoi models.

ABSTRACT: An important open question in the modeling of biological tissues is how to identify the right scale for coarse-graining, or equivalently, the right number of degrees of freedom. For confluent biological tissues, both vertex and Voronoi models, which differ only in their representation of the degrees of freedom, have effectively been used to predict behavior, including fluid-solid transitions and cell tissue compartmentalization, which are important for biological function. However, recent work in 2D has hinted that there may be differences between the two models in systems with heterotypic interfaces between two tissue types, and there is a burgeoning interest in 3D tissue models. Therefore, we compare the geometric structure and dynamic sorting behavior in mixtures of two cell types in bo

SUBMITTER: Lawson-Keister E 

PROVIDER: S-EPMC10796063 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature