Genomic epidemiology and heterogeneity of Providencia and their bla_NDM-1-carrying plasmids.

ABSTRACT: Providencia as an opportunistic pathogen can cause serious infection, and moreover the emergence of multi-drug-resistant Providencia strains poses a potentially life-threatening risk to public health. However, a comprehensive genomic study to reveal the population structure and dissemination of Providencia is still lacking. In this study, we conducted a genomic epidemiology analysis on the 580 global sequenced Providencia isolates, including 257 ones sequenced in this study (42 ones were fully sequenced). We established a genome sequence-based species classification scheme for Providencia, redefining the conventional 11 Providencia species into seven genocomplexes that were further divided into 18 genospecies, providing an extensively updated refer

SUBMITTER: Wang P 

PROVIDER: S-EPMC10796120 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature