First-line monodrug chemotherapy in low-risk gestational trophoblastic neoplasia: a network meta-analysis.

ABSTRACT:

Objective

The efficacy of the first-line monodrug chemotherapy has been generally established for low-risk GTN. Most patients can achieve a complete response after the first-line monodrug chemotherapy. However, which monodrug chemotherapy regimen is better for individual patients with GTN is not yet certain. This study aimed to assess the efficacy of first-line monodrug chemotherapy in low-risk gestational trophoblastic neoplasia (GTN).

Method

Databases, including PubMed, Embase, Web of Science, and Cochrane Library, were searched from inception to November 1, 2022, for case-control studies on first-line monodrug chemotherapy in GTN. Network meta-analysis was performed to compare the efficacy outcome of six monodrug chemotherapy regimens in GTN, with a complete response rate

SUBMITTER: Zhou F 

PROVIDER: S-EPMC10796812 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature