Impacts of ovarian reserve on conservative treatment for endometrial cancer and atypical hyperplasia.

ABSTRACT:

Objectives

Real-world data indicated that some endometrial atypical hyperplasia (EAH) and early endometrial carcinoma (EEC) patients of fertility preservation had a normal ovarian reserve, while some had a decreased ovarian reserve (DOR). This study was designed to investigate the effect of baseline ovarian reserve on the treatment of EAH and EEC patients who ask for preservation of fertility.

Methods

This was a prospective cohort study conducted at a single university-affiliated fertility center. A total of 102 EAH and EEC patients who received fertility-preserving treatment between March 2019 and August 2020 were included and divided into a DOR group (n=22) and a non-DOR group (n=80).

Results

The 32-week CR rate of the non-DOR group was significantly higher than tha

SUBMITTER: Wu P 

PROVIDER: S-EPMC10796988 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature