Mirabegron for medical expulsive therapy of ureteral stones: a systematic review and meta-analysis.

ABSTRACT:

Objective

To systematically review and quantitively evaluate the efficacy and safety of mirabegron as a medical expulsive therapy for ureteral stones.

Methods

We performed an extensive search of the EMBASE and PubMed databases for studies examining the use of mirabegron as a medical expulsive therapy for ureteral stones. The primary outcome measure assessed was the stone expulsion rate (SER), while the secondary outcomes evaluated were the stone expulsion interval (SEI) and the occurrence of pain episodes during follow-up. Risk ratios (RRs) and mean differences (MDs) with their respective 95% CIs were calculated.

Results

We included a total of seven studies involving 728 participants. Our analysis revealed a significant increase in the stone expulsion rate (SER) with

SUBMITTER: Song H 

PROVIDER: S-EPMC10797003 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature