Echo time-dependent observed T1 and quantitative perfusion in chronic obstructive pulmonary disease using magnetic resonance imaging.

ABSTRACT:

Introduction

Due to hypoxic vasoconstriction, perfusion is interesting in the lungs. Magnetic Resonance Imaging (MRI) perfusion imaging based on Dynamic Contrast Enhancement (DCE) has been demonstrated in patients with Chronic Obstructive Pulmonary Diseases (COPD) using visual scores, and quantification methods were recently developed further. Inter-patient correlations of echo time-dependent observed T₁ [T₁(TE)] have been shown with perfusion scores, pulmonary function testing, and quantitative computed tomography. Here, we examined T₁(TE) quantification and quantitative perfusion MRI together and investigated both inter-patient and local correlations between T₁(TE) and quantitative perfusion.

Methods

22 patients (age 68.0 ± 6.2)

SUBMITTER: Triphan SMF 

PROVIDER: S-EPMC10797117 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature