Automatic diagnosis of Parkinson's disease using artificial intelligence base on routine T1-weighted MRI.

ABSTRACT:

Background

Parkinson's disease (PD) is the second most common neurodegenerative disease. An objective diagnosis method is urgently needed in clinical practice. In this study, deep learning and radiomics techniques were studied to automatically diagnose PD from healthy controls (HCs).

Methods

155 PD patients and 154 HCs were randomly divided into a training set (246 patients) and a testing set (63 patients). The brain subregions identification and segmentation were automatically performed with a VB-net, and radiomics features of billateral thalamus, caudatum, putamen and pallidum were extracted. Five independent machine learning classifiers [Support Vector Machine (SVM), Stochastic gradient descent (SGD), random forest (RF), quadratic discriminant analysis (QDA) and decision

SUBMITTER: Li C 

PROVIDER: S-EPMC10797132 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature