Prognostic significance of lymph nodes assessment during pulmonary metastasectomy: a systematic review and meta-analysis.

ABSTRACT:

Background

Lung metastasectomy is an accepted treatment modality worldwide. Whether the addition of lymph node dissection to the procedure is useful remains, however, unknown.

Methods

We performed a systematic review of the literature analyzing MEDLINE, Embase, until 31st October 2021. We included all studies which met the inclusion criteria aiming to determine if the addition of lymph node tissue dissection/sampling to lung metastasectomy offers survival benefits when compared to patients who do receive lymph node tissue dissection. Secondary outcomes were 3- and 5-year overall survival (OS) and disease-free survival (DFS). Each study was assessed for risk of bias. The data collected from the included studies were pooled using reconstruction of individual-level patient data

SUBMITTER: Minervini F 

PROVIDER: S-EPMC10797341 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature