Intra-operative anesthetic induced myocardial protection during cardiothoracic surgery: a literature review.

ABSTRACT:

Background and objective

Myocardial protection involves limiting the metabolic activity and oxygen consumption of the heart, thus enabling surgery to proceed with minimal blood loss while reducing the level of ischemic injury. It was this concept that allowed for the development of the open-heart surgical technique. We know myocardial ischemia and reperfusion injury are both detrimental, thus developing strategies to mitigate this can help reduce peri-operative morbidity and mortality. In this review, we will mainly be addressing the anesthetic considerations for myocardial protection, along with discussing potential future research which can help expand the field.

Methods

We searched the PubMed database for relevant studies dating from 2004-2022. In total, 18 studies were d

SUBMITTER: Abraham AS 

PROVIDER: S-EPMC10797362 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature