Untargeted metabolomic analysis investigating links between unprocessed red meat intake and markers of inflammation.

ABSTRACT:

Background

Whether red meat consumption is associated with higher inflammation or confounded by increased adiposity remains unclear. Plasma metabolites capture the effects of diet after food is processed, digested, and absorbed, and correlate with markers of inflammation, so they can help clarify diet-health relationships.

Objective

To identify whether any metabolites associated with red meat intake are also associated with inflammation.

Methods

A cross-sectional analysis of observational data from older adults (52.84% women, mean age 63 ± 0.3 y) participating in the Multi-Ethnic Study of Atherosclerosis (MESA). Dietary intake was assessed by food-frequency questionnaire, alongside C-reactive protein (CRP), interleukin-2, interleukin-6, fibrinogen, homocysteine, and t

SUBMITTER: Wood AC 

PROVIDER: S-EPMC10797554 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature