ToxCodAn-Genome: an automated pipeline for toxin-gene annotation in genome assembly of venomous lineages.

ABSTRACT:

Background

The rapid development of sequencing technologies resulted in a wide expansion of genomics studies using venomous lineages. This facilitated research focusing on understanding the evolution of adaptive traits and the search for novel compounds that can be applied in agriculture and medicine. However, the toxin annotation of genomes is a laborious and time-consuming task, and no consensus pipeline is currently available. No computational tool currently exists to address the challenges specific to toxin annotation and to ensure the reproducibility of the process.

Results

Here, we present ToxCodAn-Genome, the first software designed to perform automated toxin annotation in genomes of venomous lineages. This pipeline was designed to retrieve the full-length coding sequ

SUBMITTER: Nachtigall PG 

PROVIDER: S-EPMC10797961 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature