Dietary supplementation of benzoic acid and essential oils combination enhances intestinal resilience against LPS stimulation in weaned piglets.

ABSTRACT:

Background

The benefits of combining benzoic acid and essential oils (BAO) to mitigate intestinal impairment during the weaning process have been well established, while the detailed underlying mechanism has not been fully elucidated. Previous research has primarily focused on the reparative effects of BAO on intestinal injury, while neglecting its potential in enhancing intestinal stress resistance.

Methods

In this study, we investigated the pre-protective effect of BAO against LPS-induced stress using a modified experimental procedure. Piglets were pre-supplemented with BAO for 14 d, followed by a challenge with LPS or saline to collect blood and intestinal samples.

Results

Our findings demonstrated that BAO supplementation led to significant improvements in piglets

SUBMITTER: Cui C 

PROVIDER: S-EPMC10797991 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature