Effects of omalizumab on lung function in patients with moderate-to-severe allergic asthma: a systematic review and meta-analysis.

ABSTRACT:

Background

With the rise of targeted treatments for asthma, treatment with omalizumab is a new option.

Objectives

To assess the improvement of pulmonary function with additional omalizumab treatment in patients (⩾6 years old) with moderate-to-severe allergic asthma.

Data sources and methods

Observational studies of randomized controlled trials of add-on omalizumab for the treatment of patients with moderate-to-severe allergic asthma, published from the establishment till August 2022, were retrieved from WAN FANG DATA, PubMed, CNKI, Embase, Cochrane, and Web of Science databases. Data extraction and quality evaluation were performed on the literature that met the inclusion criteria, using RevMan 5.3 to analyze the data.

Results

A total of 11 randomized controlle

SUBMITTER: Liao J 

PROVIDER: S-EPMC10798107 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature