Piezoelectrically and Topographically Engineered Scaffolds for Accelerating Bone Regeneration.

ABSTRACT: Bone regeneration remains a critical concern across diverse medical disciplines, because it is a complex process that requires a combinatorial approach involving the integration of mechanical, electrical, and biological stimuli to emulate the native cellular microenvironment. In this context, piezoelectric scaffolds have attracted considerable interest owing to their remarkable ability to generate electric fields in response to dynamic forces. Nonetheless, the application of such scaffolds in bone tissue engineering has been limited by the lack of a scaffold that can simultaneously provide both the intricate electromechanical environment and the biocompatibility of the native bone tissue. Here, we present a pioneering biomimetic scaffold that combines the unique properties of piezoelectric

SUBMITTER: Joo S 

PROVIDER: S-EPMC10798259 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature