Can a specific biobehavioral-based therapeutic education program lead to changes in pain perception and brain plasticity biomarkers in chronic pain patients? A study protocol for a randomized clinical trial.

ABSTRACT:

Background

Chronic pain conditions are complex multifactorial disorders with physical, psychological, and environmental factors contributing to their onset and persistence. Among these conditions, the role of brain-derived neurotrophic factor (BDNF) and the impact of a specific therapeutic education (TE) on pain management have emerged as important areas of research.

Objective

This study aims to investigate the effects of a specific type of therapeutic education on pain levels and BDNF concentrations.

Methods

In this single-blind, randomized clinical trial, patients will be randomly assigned to one of two groups: one will receive exercise with TE and the other without TE. Assessments will be made at baseline, mid-treatment, post-intervention, and at one and eight mont

SUBMITTER: Di Bonaventura S 

PROVIDER: S-EPMC10798500 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature