Comparison of hemodynamic effects of chest compression delivered via machine or human in asphyxiated piglets.

ABSTRACT:

Background

High-quality chest compressions (CC) are an important factor of neonatal resuscitation. Mechanical CC devices may provide superior CC delivery and improve resuscitation outcomes. We aimed to compare the hemodynamic effects of CC delivered by machine and human using a neonatal piglet model.

Methods

Twelve asphyxiated piglets were randomized to receive CC during resuscitation using an automated mechanical CC device ("machine") or the two-thumb encircling technique ("human"). CC was superimposed with sustained inflations.

Results

Twelve newborn piglets (age 0-3 days, weight 2.12 ± 0.17 kg) were included in the study. Machine-delivered CC resulted in an increase in stroke volume, and minimum and maximum rate of left ventricle pressure change (dp/dt_min

SUBMITTER: O'Reilly M 

PROVIDER: S-EPMC10798894 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature