Lung ultrasound detects regional aeration inhomogeneity in ventilated preterm lambs.

ABSTRACT:

Background

Inhomogeneous lung aeration is a significant contributor to preterm lung injury. EIT detects inhomogeneous aeration in the research setting. Whether LUS detects inhomogeneous aeration is unknown. The aim was to determine whether LUS detects regional inhomogeneity identified by EIT in preterm lambs.

Methods

LUS and EIT were simultaneously performed on mechanically ventilated preterm lambs. LUS images from non-dependent and dependent regions were acquired and reported using a validated scoring system and computer-assisted quantitative LUS greyscale analysis (Q-LUS_MGV). Regional inhomogeneity was calculated by observed over predicted aeration ratio from the EIT reconstructive model. LUS scores and Q-LUS_MGV were compared with EIT aeration ratios

SUBMITTER: He LLH 

PROVIDER: S-EPMC10798896 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature