Micromotor-based dual aptassay for early cost-effective diagnosis of neonatal sepsis.

ABSTRACT: Given the long-life expectancy of the newborn, research aimed at improving sepsis diagnosis and management in this population has been recognized as cost-effective, which at early stages continues to be a tremendous challenge. Despite there is not an ideal-specific biomarker, the simultaneous detection of biomarkers with different behavior during an infection such as procalcitonin (PCT) as high specificity biomarker with one of the earliest biomarkers in sepsis as interleukin-6 (IL-6) increases diagnostic performance. This is not only due to their high positive predictive value but also, since it can also help the clinician to rule out infection and thus avoid the use of antibiotics, due to their high negative predictive value. To this end, we explore a cutting-edge micromotor (MM)-based O

SUBMITTER: Gordon Pidal JM 

PROVIDER: S-EPMC10798920 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature