Adaptable test bench for ASTM-compliant permeability measurement of porous scaffolds for tissue engineering.

ABSTRACT: Intrinsic permeability describes the ability of a porous medium to be penetrated by a fluid. Considering porous scaffolds for tissue engineering (TE) applications, this macroscopic variable can strongly influence the transport of oxygen and nutrients, the cell seeding process, and the transmission of fluid forces to the cells, playing a crucial role in determining scaffold efficacy. Thus, accurately measuring the permeability of porous scaffolds could represent an essential step in their optimization process. In literature, several methods have been proposed to characterize scaffold permeability. Most of the currently adopted approaches to assess permeability limit their applicability to specific scaffold structures, hampering protocols standardization, and ultimately leading to incomparab

SUBMITTER: Gabetti S 

PROVIDER: S-EPMC10799031 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature