Metabolic syndrome increases osteoarthritis risk: findings from the UK Biobank prospective cohort study.

ABSTRACT:

Objective

The association between Metabolic Syndrome (MetS), its components, and the risk of osteoarthritis (OA) has been a topic of conflicting evidence in different studies. The aim of this present study is to investigate the association between MetS, its components, and the risk of OA using data from the UK Biobank.

Methods

A prospective cohort study was conducted in the UK Biobank to assess the risk of osteoarthritis (OA) related to MetS. MetS was defined according to the criteria set by the International Diabetes Federation (IDF). Additionally, lifestyle factors, medications, and the inflammatory marker C-reactive protein (CRP) were included in the model. Cox proportional hazards regression was used to calculate hazard ratios (HR) and 95% confidence intervals (CI). The

SUBMITTER: Zhang S 

PROVIDER: S-EPMC10799367 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature