Ontology highlight
ABSTRACT:
SUBMITTER: Wang PF
PROVIDER: S-EPMC10799425 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
Wang Peng-Fei PF Jiang Fei F Zeng Qiu-Ming QM Yin Wei-Fan WF Hu Yue-Zi YZ Li Qiao Q Hu Zhao-Lan ZL
Journal of neuroinflammation 20240120 1
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by the infiltration of inflammatory cells and demyelination of nerves. Mitochondrial dysfunction has been implicated in the pathogenesis of MS, as studies have shown abnormalities in mitochondrial activities, metabolism, mitochondrial DNA (mtDNA) levels, and mitochondrial morphology in immune cells of individuals with MS. The presence of mitochondrial dysfunctions in immune cells contributes to immunological dysregulation and ...[more]