The association between prolonged capillary refill time and microcirculation changes in children with sepsis.

ABSTRACT:

Backgrounds

In children with sepsis, circulatory shock and multi-organ failure remain major contributors to mortality. Prolonged capillary refill time (PCRT) is a clinical tool associated with disease severity and tissue hypoperfusion. Microcirculation assessment with videomicroscopy represents a promising candidate for assessing and improving hemodynamic management strategies in children with sepsis. Particularly when there is loss of coherence between the macro and microcirculation (hemodynamic incoherence). We sought to evaluate the association between PCRT and microcirculation changes in sepsis.

Methods

This was a prospective cohort study in children hospitalized with sepsis. Microcirculation was measured using sublingual video microscopy (capillary density and flow and

SUBMITTER: Fernandez-Sarmiento J 

PROVIDER: S-EPMC10799439 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature