Therapeutic applications of gut microbes in cardiometabolic diseases: current state and perspectives.

ABSTRACT: Cardiometabolic disease (CMD) encompasses a range of diseases such as hypertension, atherosclerosis, heart failure, obesity, and type 2 diabetes. Recent findings about CMD's interaction with gut microbiota have broadened our understanding of how diet and nutrition drive microbes to influence CMD. However, the translation of basic research into the clinic has not been smooth, and dietary nutrition and probiotic supplementation have yet to show significant evidence of the therapeutic benefits of CMD. In addition, the published reviews do not suggest the core microbiota or metabolite classes that influence CMD, and systematically elucidate the causal relationship between host disease phenotypes-microbiome. The aim of this review is to highlight the complex interaction of the gut microbiota an

SUBMITTER: Yuan L 

PROVIDER: S-EPMC10799778 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature