Geographical variation in treated psychotic and other mental disorders in Finland by region and urbanicity.

ABSTRACT:

Purpose

In Finland, prevalence of schizophrenia is higher in the eastern and northern regions and co-occurs with the distribution of schizophrenia polygenic risk scores. Both genetic and environmental factors have been hypothesized to contribute to this variation. We aimed to examine the prevalence of psychotic and other mental disorders by region and degree of urbanicity, and the impacts of socio-economic adjustments on these associations.

Methods

Nationwide population registers from 2011 to 2017 and healthcare registers from 1975 to 2017. We used 19 administrative and three aggregate regions based on the distribution of schizophrenia polygenic risk scores, and a seven-level urban-rural classification. Prevalence ratios (PRs) were calculated by Poisson regression models and

SUBMITTER: Suokas K 

PROVIDER: S-EPMC10799825 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature