Effect of physiological and pharmacological stress on heart rate, blood pressure, and echocardiographic measurements in healthy Warmblood horses.

ABSTRACT:

Background

Echocardiographic measurements are important prognostic indicators but might be influenced by heart rate and blood pressure. This is particularly important when comparing repeated examinations.

Hypothesis

To determine the effect of physiological stress at mildly increased heart rates and pharmacological challenge using IV administration of N-butylscopolammonium bromide and metamizol sodium on heart rate, blood pressure, and echocardiographic measurements.

Animals

Twenty healthy Warmblood horses.

Methods

Randomized crossover study. Horses were examined echocardiographically by 2-dimensional, M-mode, pulsed wave (PW) Doppler, and PW tissue Doppler imaging with simultaneous ECG recording and noninvasive blood pressure measurements during rest, physiolog

SUBMITTER: Dufourni A 

PROVIDER: S-EPMC10800213 | biostudies-literature | 2024 Jan-Feb

REPOSITORIES: biostudies-literature