Clinical relevance of serum ionized magnesium concentration in dogs with myxomatous mitral valve disease.

ABSTRACT:

Background

Hypomagnesemia is associated with a poor prognosis in humans with congestive heart failure (CHF), but studies in veterinary medicine are limited.

Hypothesis

Serum ionized magnesium concentration [iMg²⁺ ] would decrease as CHF progresses compared with the initial diagnostic levels and that lower [iMg²⁺ ] would be negatively associated with prognosis in dogs with CHF.

Animals

A total of 181 client-owned dogs with myxomatous mitral valve disease (MMVD) were included. They were classified into the preclinical stage (NO-CHF, n = 108), stage C (n = 42), and stage D (n = 31) based on the American College of Veterinary Internal Medicine MMVD classification.

Methods

This is a retrospective study from 2 referral centers. The [iMg^2+</

SUBMITTER: Kim OK 

PROVIDER: S-EPMC10800217 | biostudies-literature | 2024 Jan-Feb

REPOSITORIES: biostudies-literature