Association of serum levels of inflammatory cytokines with retinopathy of prematurity in preterm infants.

ABSTRACT:

Introduction

Retinopathy of prematurity (ROP) is a retinal vascular developmental disease associated with risks factors such as supplementary oxygen use or low birth weight/early gestational age. Multiple studies have reported associations between ROP and systemic inflammation. In this study, we investigated serum cytokines associated with ROP development and severity and assessed their applicability as potential biomarkers of ROP.

Methods

This prospective study was conducted at an institutional referral center between 2019 and 2021. To measure the serum levels of 40 inflammatory cytokines in eligible premature patients, we collected their serum samples during the enrollment of patients or the intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents an

SUBMITTER: Ling XC 

PROVIDER: S-EPMC10800500 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature