Anxiety disorders and adhesive capsulitis: a bidirectional Mendelian randomization study.

ABSTRACT:

Background

Previous epidemiological investigations and related research efforts consistently have outlined an observable association between anxiety disorders and adhesive capsulitis (AC). However, the intricate nature of the causal connection between these entities has yet to be fully clarified. Therefore, this investigative study aims to thoroughly examine and delineate the causal interrelationship between anxiety disorders and AC using a bidirectional, two-sample Mendelian randomization (MR) approach.

Methods

To pursue this inquiry, datasets related to anxiety disorders and AC were meticulously obtained from a publicly accessible genomewide association study. Instrumental variables, in the form of single nucleotide polymorphisms, were subsequently identified, undergoing a

SUBMITTER: Ouyang Y 

PROVIDER: S-EPMC10800800 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature