Associations between urinary phthalate concentrations and antral follicle count among women undergoing in vitro fertilization.

ABSTRACT:

Background

Phthalates are ubiquitously used in a variety of products and have an adverse effect on folliculogenesis. However, previous epidemiological studies on the associations between phthalate exposure and antral follicle count (AFC) produced conflicting results. The present study aimed to evaluate the associations between urinary phthalate metabolite concentrations and AFC among women undergoing in vitro fertilization (IVF).

Methods

We collected 525 urine samples and measured 8 phthalate metabolites from IVF patients. Poisson regression models were conducted to evaluate the associations between phthalate metabolite concentrations and AFC. In addition, participants were stratified into a younger group (< 35 years) and an older group (≥ 35 years) to explore the pot

SUBMITTER: Yao Y 

PROVIDER: S-EPMC10801055 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature