Predictive role of selected biomarkers in differentiating gram-positive from gram-negative sepsis in surgical patients: a retrospective study.

ABSTRACT:

Introduction

Patients after major surgery are at high risk of developing sepsis, which is accompanied by elevated serum levels of C-reactive protein (CRP) and procalcitonin (PCT). This study aimed to examine the differences in serum biomarker levels concerning the causative agent of sepsis in surgical patients.

Material and methods

A retrospective study was carried out in the surgical intensive care unit (ICU) and included 81 septic patients admitted from January 2019 to May 2022, who had positive blood cultures (BC). Serum levels of PCT, CRP, white blood cells (WBC) and platelet counts were recorded on the day of the positive BC and over the following 3 days.

Results

Patients with gram(-) sepsis had significantly higher PCT levels, and lower platelet count compared t

SUBMITTER: Neskovic N 

PROVIDER: S-EPMC10801538 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature