Dose-Escalated Radiation Therapy as Primary Treatment for Residual Bladder Cancer After Transurethral Resection.

ABSTRACT:

Purpose

The aim of this study was to determine whether escalating the local radiation dose can improve the outcome of residual bladder cancer after transurethral resection of bladder tumor without increasing treatment-related toxicity.

Methods and materials

The treatment plans and medical records of patients with bladder cancer treated with curative-intent radiation therapy between 2008 and 2020 were reviewed. Those who had residual tumors in the computed tomography simulation images were included. A cumulative radiation dose higher than 6600 cGy was defined as dose escalation. The effect of dose escalation on 3-year locoregional control, progression-free survival, and overall survival was evaluated.

Results

A total of 149 patients with residual tumors were identified

SUBMITTER: Chang YC 

PROVIDER: S-EPMC10801638 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature