Cystic Brain Metastasis Outcomes After Gamma Knife Radiation Therapy.

ABSTRACT:

Purpose

The response of cystic brain metastases (BMets) to radiation therapy is poorly understood, with conflicting results regarding local control, overall survival, and treatment-related toxicity. This study aims to examine the role of Gamma Knife (GK) in managing cystic BMets.

Methods and materials

Volumetric analysis was conducted to measure tumor and edema volume at the time of GK and follow-up magnetic resonance imaging studies. Survival was described using the Kaplan-Meier method, and the cumulative incidence of progression was described using the Aalen-Johansen estimator. We evaluated the association of 4 variables with survival using Cox regression analysis.

Results

Between 2016 and 2021, 54 patients with 83 cystic BMets were treated with GK at our institutio

SUBMITTER: Amidon RF 

PROVIDER: S-EPMC10801666 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature