Metagenomics reveals the temporal dynamics of the rumen resistome and microbiome in goat kids.

ABSTRACT:

Background

The gut microbiome of domestic animals carries antibiotic resistance genes (ARGs) which can be transmitted to the environment and humans, resulting in challenges of antibiotic resistance. Although it has been reported that the rumen microbiome of ruminants may be a reservoir of ARGs, the factors affecting the temporal dynamics of the rumen resistome are still unclear. Here, we collected rumen content samples of goats at 1, 7, 14, 28, 42, 56, 70, and 84 days of age, analyzed their microbiome and resistome profiles using metagenomics, and assessed the temporal dynamics of the rumen resistome in goats at the early stage of life under a conventional feeding system.

Results

In our results, the rumen resistome of goat kids contained ARGs to 41 classes, and the richness

SUBMITTER: Chai J 

PROVIDER: S-EPMC10801991 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature