Two Distinct Regulatory Systems Control Pulcherrimin Biosynthesis in Bacillus subtilis.

ABSTRACT: Regulation of transcription is a fundamental process that allows bacteria to respond to external stimuli with appropriate timing and magnitude of response. In the soil bacterium Bacillus subtilis, transcriptional regulation is at the core of developmental processes needed for cell survival. Gene expression in cells transitioning from exponential phase to stationary phase is under the control of a group of transcription factors called transition state regulators (TSRs). TSRs influence numerous developmental processes including the decision between biofilm formation and motility, genetic competence, and sporulation, but the extent to which TSRs influence bacterial physiology remains to be fully elucidated. Here, we demonstrate two TSRs, ScoC and AbrB, along with the MerR-family transc

SUBMITTER: Fernandez NL 

PROVIDER: S-EPMC10802322 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature