Structural and functional connectivity associations with anterior cingulate sulcal variability.

ABSTRACT:

Background

Sulcation of the anterior cingulate may be defined by presence of a paracingulate sulcus, a tertiary sulcus developing during the third gestational trimester with implications on cognitive function and disease.

Methods

In this retrospective analysis we examine task-free resting state functional connectivity and diffusion-weighted tract segmentation data from a cohort of healthy adults (< 60-year-old, n = 129), exploring the impact of ipsilateral paracingulate sulcal presence on structural and functional connectivity.

Results

Presence of a left paracingulate sulcus was associated with reduced fractional anisotropy in the left cingulum (P = 0.02) bundle and the peri-genual (P = 0.002) and dorsal (P = 0.03) but not the temporal cingulum bu

SUBMITTER: Harper L 

PROVIDER: S-EPMC10802698 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature